ea0041ep1018 | Thyroid (non-cancer) | ECE2016
Chung Jae Hoon
, Kim Sun Wook
, Kim Hye Jeong
, Sohn Seo Young
, Kim Young Nam
, Lee You-Bin
, Kim Hye-In
, Lee Seung-Eun
Background: Three deiodinase genes (DIO) play an important role in thyroid hormone metabolism. Among them, type 2 iodothyronine deiodinase (DIO2) converts T4 to T3 in brain and impaired psychological well-being was reported in minor variants of DIO2. However, the prevalence of three DIOs and their relation to neuropsychological status has not been evaluated in Asian hypothyroid subjects.Methods: We prospectively enrolled 196 subjects who were taking levo...